Piperacillin induced bone marrow suppression: a case report

نویسندگان

  • Ashish Kumar
  • Gourdas Choudhuri
  • Rakesh Aggarwal
چکیده

BACKGROUND Piperacillin (and piperacillin/tazobactam) is a commonly prescribed antibiotic and is generally considered safe. We report a case of piperacillin induced bone marrow suppression. CASE PRESENTATION A 19-year-old boy was being treated with piperacillin followed by piperacillin/tazobactam for infected pancreatic pseudocyst. After 21 days of treatment, he developed neutropenia and thrombocytopenia. These reversed promptly after stopping piperacillin/tazobactam. The time course of events suggested that piperacillin was the cause of bone marrow suppression in this patient. CONCLUSION Bone marrow suppression is a serious adverse effect of piperacillin, which should be kept in mind while treating patients with this drug.

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عنوان ژورنال:
  • BMC Clinical Pharmacology

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2003